Sickle Cell Anemia
The sickle cell trait is a genetically linked, inherited condition. Inheritance cannot be prevented, but it may be predicted. Screening is recommended for individuals in high-risk populations; in the United States, African Americans and Hispanic Americans have the highest risk of being carriers.
Screening at birth offers the opportunity for early intervention; more than 40 states include sickle cell screening as part of the usual battery of blood tests done for newborns. Pregnant women and couples planning to have children may also wish to be screened to determine their carrier status. Carriers have a 50% chance of passing the trait to their offspring. Children born to two carriers have a 25% chance of inheriting the trait from both parents and having sickle cell anemia. Carriers may consider genetic counseling to assess any risks to their offspring. The sickle cell trait can also be identified through prenatal testing; specifically through use of amniotic fluid testing or chorionic villus sampling.
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Science EncyclopediaScience & Philosophy: Semiotics to SmeltingSickle Cell Anemia - Hemoglobin Structure, Sickle Cell Hemoglobin, Sickle Cell Anemia, Affected Populations, Causes And Symptoms - Delayed growth, Acute chest syndrome, Treatment, Alternative treatment