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Varicella Zoster Virus

chickenpox shingles occurs envelope

Varicella zoster virus is a member of the alphaherpesvirus group and is the cause of both chickenpox (also known as varicella) and shingles (herpes zoster).

The virus is surrounded by a covering, or envelope, that is made of lipid. As such, the envelope dissolves readily in solvents such as alcohol. Wiping surfaces with alcohol is thus an effective means of inactivating the virus and preventing spread of chickenpox. Inside the lipid envelope is a protein shell that houses the deoxyribonucleic acid.

Varicella zoster virus is related to herpes simplex viruses types 1 and 2. Indeed, nucleic acid analysis has revealed that the genetic material of the three viruses is highly similar, both in the genes present and in the arrangement of the genes.

Chickenpox is the result of a person's first infection with the virus. Typically, chickenpox occurs most often in children. Recovery is usually complete within a week or two and immunity to another bout of chickenpox is usually, but not always, life-long. Treatment for chickenpox is available. Fortunately for adults, a vaccine to chickenpox exists for those who have not contracted chickenpox in their childhood.

Naturally acquired immunity to chickenpox does not prevent someone from contracting shingles years, even decades later. Shingles occurs in between 10% and 20% of those who have had chickenpox. In the United States, upwards of 800,000 people are afflicted with shingles each year. The annual number of shingles sufferers worldwide is in the millions. The disease occurs most commonly in those who are over 50 years of age.

As the symptoms of chickenpox fade, varicella zoster virus is not eliminated from the body. Rather, the virus lies dormant in nerve tissue, particularly in the face and the body. The roots of sensory nerves in the spinal cord are also a site of virus hibernation. The virus is stirred to replicate by triggers that are as yet unclear. Impairment of the immune system seems to be involved, whether from immunodeficiency diseases or from cancers, the effect of drugs, or a generalized debilitation of the body with age. Whatever forces of the immune system that normally operate to hold the hibernating virus in check are abrogated.

Reactivation of the virus causes pain and a rash in the region that is served by the affected nerves. The affected areas are referred to as dermatomes. These areas appear as a rash or blistering of the skin. This can be quite painful during the one to two weeks they persist. Other complications can develop. For example, shingles on the face can lead to an eye infection causing temporary or even permanent blindness. A condition of muscle weakness or paralysis, known as Guillian-Barre syndrome, can last for months after a bout of shingles. Another condition known as post herpetic neuralgia can extend the pain of shingles long after the visible symptoms have abated.

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8 months ago

Good-day to everyone in this site i want to use this means to also tell the world about doctor ABEGBE the man sent to this earth to help those who are in need, i was very sick all this years without solution i have try many means to get my self cured but nothing work out, so today i am here to also tell this to the people in this site that there is cure to this HSV 2, i was able to reach this man through the means of a friend from UK called Sophia but i live in United state, i am very happy writing this,my friend told me that she meet this man personally when she travel to Africa because of this same sickness and i was so surprise to hear that from her, she explain everything about this man cure to me, that there is herbal cure and curing spell and that was the first time i hear about curing spell, so i ask her which of the cure do you go for she told that, it was the herbal cured. she traveled there and she spend 1 week and 4 days with the doctor so before she could know she was cured totally and he decide to go for test over there before traveling back home, her result was negative and even when she get home her result remain negative i was so surprise about what she told me, i have that confidence to contact the doctor, and applied for the herbal immediately so the doctor sent me the herbal here in US, and i used it according to the way the Dr instructed, now i am cured and free from HSV2 if you want to reach this doctor just email him now DR.ABEGBESPELLHOME@GMAIL.COM OR DR.ABEGBESPELLHOME@HOTMAIL.COM
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almost 8 years ago

The important thing is to see some one as soon as possible once blisters appear.

I presently have shingles still with the blisters , last week I experienced shooting pulsing pains in my back and groin but no rash . I was given pain killers.

4 days later being a Sunday and now with some painful blisters visible I took myself off to the hospital. A doctor prescibed pain killers with a laxative , I queried whether I should have an antiviral treatment? i had no confidence in the doc and saw my Doctor on the Monday who confirmed Shingles and prescribed antiviral treatment .

The pain eases.