Sodium Benzoate - Production

There are three methods for the commercial preparation of sodium benzoate. In one method, naphthalene is oxidized with vanadium pentoxide to give phthalic anhydride. This is decarboxylated to yield benzoic acid. In a second method, toluene is mixed with nitric acid and oxidized to produce benzoic acid. In a third method, benzotrichloride is hydrolyzed and then treated with a mineral acid to give benzoic acid. Benzotrichloride is formed by the reaction of chlorine and toluene. In all cases, the benzoic acid is further refined to produce sodium benzoate. One way this is done is by dissolving the acid in a sodium hydroxide solution. The resulting chemical reaction produces sodium benzoate and water. The crystals are isolated by evaporating off the water.

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User Comments Add a comment…

over 1 year ago

Netta » shplen1 ((at)) walla dot co dot il

Hello,

I'm looking for a way to sterilize Sodium Benzoate in order to give it to a patient.

The problem is that Sodium Benzoate, as it is written in other sources, is heat-sensitive, therefore what way is recommended in order to do so, and in a small amount (for one patient)?

Thank you very much.