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Reye's Syndrome

aspirin children viral brain

Reye's syndrome is a serious medical condition associated with viral infection and aspirin intake. It usually strikes children under age 18, most commonly those between the ages of five and 12. Symptoms of Reye's syndrome develop after the patient appears to have recovered from the initial viral infection. Symptoms include fatigue, irritability, and severe vomiting. Eventually, neurological symptoms such as delirium and coma may appear. One third of all Reye's syndrome patients die, usually from heart failure, gastrointestinal bleeding, kidney failure, or cerebral edema (a condition in which fluid presses on the brain, causing severe pressure and compression).

Reye's syndrome is a particularly serious disease because it causes severe liver damage and swelling of the brain, a condition called encephalopathy. Recovery from the illness is possible if it is diagnosed early. Even with early diagnosis, some patients who survive Reye's syndrome may have permanent neurological damage, although this damage can be subtle.

Reye's syndrome was discovered in 1963 by Dr. Ralph D. Reye. However, the connection between aspirin and viral infection was not made until the 1980s. In a study conducted by the Centers for Disease Control, 25 out of 27 children who developed Reye's syndrome after a bout with chicken pox had taken aspirin during their illness. In 140 of the children with chicken pox who had not taken aspirin, only 53 developed Reye's syndrome. Researchers are still unsure about the exact mechanism that causes aspirin to damage the liver and brain during viral infections. Some researchers suspect that aspirin inhibits key enzymes in the liver, leading to liver malfunction. However, why the combination of aspirin intake and viral infection may lead to Rye's syndrome has never been fully explained.

Since the early 1980s, public health officials and physicians have warned parents about giving children aspirin to reduce pain during viral infections. As a result of these warnings, the numbers of cases of Reye's syndrome have dropped significantly: in 1977, 500 cases were reported; in 1989, only 25 cases were reported. Nonaspirin pain relievers, such as acetaminophen, are recommended for children and teenagers. Although children represent the majority of Reye's syndrome patients, adults can also develop Reye's syndrome. Therefore, pain relief for cold and flu symptoms, as well as for other viral infections such as chicken pox and mumps, should be restricted to nonaspirin medications in both children and adults.

Kathleen Scogna

KEY TERMS

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Cerebral edema

—A condition in which fluid presses on the brain, causing severe pressure and compression.

Encephalopathy

—Any abnormality in the structure or function of the brain.

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about 1 month ago

Hello, Could this common airborne pathogen cause Reye’s Syndrome? The infection mimics the flu. My coworkers and I, all immunocompetent, got Disseminated Histoplasmosis in DFW from roosting bats, that shed it in their feces. Doctors said we couldn't possibly have it. The doctors were wrong. I read it causes hypervascularization, calcifications, sclerosis, fibrosis, necrosis, leukopenia, anemia, neutrophilia, pancytopenia, thrombocytopenia, hypoglycemia, polyps, stenosis, and perforations, inflammation of various organs, GI problems, hepatitis, etc. More than 100 outbreaks have occurred since 1938, and those are just the ones that were figured out, since people go to different doctors. One outbreak was over 100,000 victims in Indianapolis. It at least “mimics” autoimmune diseases, cancer, mental illness, migraines, seizures, etc. It’s known to cause rheumatological conditions, inflammation, and precancerous conditions. It can cause various diseases/conditions of unknown cause, for example, a certain kind of rash. It causes hematological malignancies, and some doctors claim their leukemia patients go into remission when given antifungal. My friend in another state who died from lupus lived across the street from a bat colony. It’s known to cause delusions, wild mood swings, and hallucinations. I believe the “side effects” of Haldol, leukopenia and MS symptoms, are not side effects but just more symptoms of Disseminated Histoplasmosis, since it causes leukopenia and MS symptoms. What about the unknown reason why beta blockers cause tardive dyskinesia? The tinnitus, photophobia, psychosis "caused" by Cipro? The hypersexuality and leukemia "caused” by Abilify? It's most potent in female lactating bats, because the fungus likes sugar (lactose) and nitrogen (amino acids, protein). What about female lactating humans…postpartum psychosis? The bats give birth late spring/summer, and I noticed suicide rates spike in late spring/early summer? A map of mental distress appears to almost perfectly overlay a map of Histoplasmosis. Apparently, even the CDC didn’t know bats CARRY it and shed it in their feces. Researchers claim the subacute type is more common than believed. It is known to at least mimic autoimmune diseases and cancer, and known to give false-positives in PET scans. But no one diagnosed with an autoimmune disease or cancer is screened for it. In fact, at least one NIH paper states explicitly that all patients diagnosed with sarcoidosis be tested for it, but most, if not all, are not. 80-90+% of people in some areas have been infected. Other doctors are claiming things like sarcoidosis is disseminated histoplasmosis, and researchers are claiming subacute disseminated histoplasmosis is much more common in immunocompetent people than previously believed. My coworkers and I had GI problems, liver problems, weird rashes, plantar fasciitis, etc., and I started getting migraines and plantar fasciitis in the building, and haven't had them since I left. It gave me seizures and benign paroxysmal positional vertigo.
There’s a lot more. I wrote a book about my experience with Disseminated Histoplasmosis called “Batsh#t Crazy,” because bats shed the fungus in their feces.