Hodgkin's Disease - The Lymphatic System, Cancer, Causes And Symptoms Of Hodgkin's Lymphoma, Diagnosis, Treatment - Prognosis
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Hodgkin's disease is a type of cancer involving tissues of the lymphatic system. The lymphatic system is a network of organs, tissues, and ducts in the human body. The lymphatic system maintains the fluid balance in the body by coordinating the draining of fluid from cells and tissues back into the bloodstream. Also, the lymphatic system aids in fighting infections caused by microorganisms, by supplying the body with white blood cells.
A variety of cancers called lymphomas affect the lymph tissues. Hodgkin's disease represents a specific type of lymphoma. Its cause is unknown, although some interaction between individual genetic makeup, environmental exposures, and infectious agents is suspected.
Hodgkin's lymphoma can occur at any age. The majority of all cases of Hodgkin's lymphoma occur in people between the ages of 15 and 34, and those who are older than 60 years of age.
Hodgkin's is one of the most curable forms of cancer. Current treatments are quite effective. Children have a particularly high rate of cure from the disease, with about 75% still living cancer-free 20 years after the original diagnosis. Adults with the most severe form of the disease have about a 50% cure rate.
Resources
Books
Jaffe, E.S., N.L. Harris, H. Stein, et al. Pathology and Genetics of Tumours of the Haematopoietic and Lymphoid Tissues. Lyon: IARC Press, 2001.
Organizations
The Leukemia and Lymphoma Society. 1311 Mamaroneck Ave. White Plains, NY 10605 (914) 949–5213 [cited November 19, 2002]. <http://www.leukemia-lymphoma.org>.
Additional Topics
The lymphatic system is part of the body's immune system. It consists of a number of elements. First, there is a network of vessels. The vessels drain tissue fluid from all the major organs of the body, including the skin, and from all four limbs. These vessels pass through lymph nodes on their way to empty their contents into major veins at the base of the neck and within the abdomen. The …
Cancer is a general term that refers to a condition in which a particular type of cell within the body begins to multiply in an out-of-control fashion. This may mean that cancer cells multiply more quickly, or it may mean that cancer cells take on abnormal characteristics. For example, at a very early stage in embryonic development (development of a fetus within the uterus), generic body cells beg…
Hodgkin's lymphoma usually begins in a lymph node. This node enlarges, but may or may not cause the pain that typically results when lymph nodes enlarge as a consequence of an infection by a microorganism. Hodgkin's lymphoma progresses in a fairly predictable way, traveling from one group of lymph nodes on to the next. More advanced cases of Hodgkin's include involvement of th…
As with many forms of cancer, diagnosis of Hodgkin's disease has two important components. First is the identification of Hodgkin's lymphoma as the cause of the patient's disease. Second is the staging of the disease; that is, an attempt to identify the degree of spread of the lymphoma. Diagnosis of Hodgkin's lymphoma requires removal of a sample of a suspicious lymph n…
Treatment of Hodgkin's lymphoma has become increasingly effective over the years. The type of treatment used for Hodgkin's depends on the information obtained by staging, and may include chemotherapy (treatment with a combination of drugs), and /or radiotherapy (treatment with x rays which kill cancer cells). Both chemotherapy and radiotherapy often have side effects. Chemotherapy ca…
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